Celrixafor 24mg injection is an antineoplastic containing the active ingredient Plerixafor. It is used in collecting blood stem cells, storage, and transplantation. It is also used in lymphoma (WBC cancer), multiple myeloma (plasma cell cancer in bone marrow), or a solid tumor. Talk to your doctor if you have or had any heart disease. Before starting the treatment, notify your doctor if you have high WBC counts, low platelet counts, or a history of usual lightheaded or fainting, especially before injection. It is not advised to take this medicine for stem cell mobilization if you have leukemia. 

Do not take this tablet if you are allergic to Plerixafor or any other medicine ingredients. Notify your doctor if you have kidney disorders; your doctor may adjust the dose of the Celrixafor 24mg if you have existing kidney disease. Your doctor may also perform a regular blood test to monitor the blood cell count. Do not take this tablet if you are pregnant or planning to get pregnant or think you might be pregnant, or if you are breastfeeding. It is recommended to use effective contraception. Report to your doctor if you experience any side effects like rashes or swelling around your eyes, a change in breathing (lack of oxygen), or pain in the abdomen (upper left) or left shoulder.

Collect blood stem cells.

Lymphoma and multiple myeloma in adults.

Lymphoma or solid tumors in children (aged between 1 to 18).

Celrixafor 24mg injection works by blocking a protein called CXCR4 (chemokine receptor) on stem cells, which helps them move from the bone marrow into the bloodstream. By blocking CXCR4, Celrixafor 24mg causes the stem cells to be released into the bloodstream, where the stem cells can be collected and isolated using a machine and stored for transplantation.

Celrixafor 24mg injection is administered as a subcutaneous injection (under your skin). If this drug is recommended for you, it will be given by a doctor. Do not self-administer. Your doctor will choose the dosage and administration frequency based on the condition because it differs from person to person.

Rashes and swelling around the eyes

Difficulty in breathing

Faintness

Upper left abdomen pain

Left shoulder pain

Diarrhea

Redness or irritation in the injection site

Low RBC count (anemia)

Constipation, indigestion

Dry mouth, numbness

Joint pains

Sweating

Difficulty in sleeping

Headache

Inform your healthcare professional about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, and herbal products. Certain medications interacting with Celrixafor 24mg may reduce effectiveness by causing undesirable side effects.

Store below 30°C

Do not refrigerate or freeze.

Keep Celrixafor 24mg injection out of sight and reach of children and pets.

You need to tell your doctor if you have any kidney disorders before taking Celrixafor 24mg Injection. Your physician may decide to adjust the dose or delay treating you depending on your kidney function. Please consult your doctor before starting this injection, and getting suggestions about fertility concerns from your doctor is recommended. Your doctor may take regular blood tests to monitor your liver function and blood cell count.