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Cold-Chain & Storage Reference Guide

Does Keytruda Need Fridge?
Cancer Medicine Storage & Expiry Guide

Search 40+ cancer injections, immunotherapies, and oral tablets. Check exact refrigeration rules (2°C-8°C), light sensitivity, shelf-life, and what to do if medicine was left out. Sourced and cold-chain guaranteed by Critical Kare Pharma.

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Was your medicine accidentally left out or ice packs melted?

Do not freeze it. Freezing forms micro-crystals that permanently destroy biologic antibodies. Immediately place the vial back in your refrigerator (2°C-8°C), record the approximate number of hours it was at room temperature, and contact our pharmacist on WhatsApp with your batch/lot number.

Emergency Rx Help
Injection / Infusion

Keytruda

Pembrolizumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Use within 24 hours at room temp or 96 hours refrigerated after dilution.
Handling Note:If warm for >4 hours, contact pharmacist immediately with lot number. Never freeze.
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Injection / Infusion

Herceptin

Trastuzumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Reconstituted solution stable 28 days at 2°C-8°C with bacteriostatic water.
Handling Note:Unreconstituted powder has limited tolerance; verify room-temp cumulative hours with pharmacist.
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Injection / Infusion

Opdivo

Nivolumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Infusion bag stable up to 24 hours (8 hours room temp, remaining refrigerated).
Handling Note:Do not shake. If vial arrived room temp, check TempTale logger readout before administration.
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Injection / Infusion

Avastin

Bevacizumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Diluted infusion solution stable up to 48 hours at 2°C-8°C.
Handling Note:Do not use if precipitate or discoloration is present. Do not freeze.
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Oral Tablet / Capsule

Tagrisso

Osimertinib

Room Temp
Target Storage Temp:20°C to 25°C (68°F to 77°F)
Light Sensitive:Standard protection
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:N/A (oral tablets). Keep blister sealed until ingestion.
Handling Note:Store in original blister away from humid bathrooms and direct dashboard heat.
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Oral Tablet / Capsule

Revlimid

Lenalidomide

Room Temp
Target Storage Temp:20°C to 25°C (68°F to 77°F)
Light Sensitive:Standard protection
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:N/A (hazardous oral capsule). Do not crush, chew, or open capsules.
Handling Note:Store safely out of reach of children and pregnant individuals due to teratogenicity.
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Injection / Infusion

Tecentriq

Atezolizumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Diluted bag stable 24 hours at 2°C-8°C or 8 hours at room temp.
Handling Note:Protect from light in original carton. Check temperature log before mixing.
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Injection / Infusion

Imfinzi

Durvalumab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Infusion preparation stable up to 24 hours refrigerated or 4 hours at room temp.
Handling Note:Store in refrigerator. Do not freeze or vigorously shake the vial.
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Oral Tablet / Capsule

Imbruvica

Ibrutinib

Room Temp
Target Storage Temp:20°C to 25°C (68°F to 77°F)
Light Sensitive:Standard protection
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:N/A (oral tablets/capsules).
Handling Note:Excursions permitted between 15°C and 30°C (59°F to 86°F).
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Injection / Infusion

Rituxan

Rituximab

Keep in Fridge
Target Storage Temp:2°C to 8°C (36°F to 46°F)
Light Sensitive:Yes — Keep in outer carton
Freezing Allowed:STRICTLY NO (Do Not Freeze)
After Opening/Dilution:Diluted solutions stable 24 hours refrigerated and 12 hours at room temp.
Handling Note:Do not freeze. Keep vial in carton until time of preparation.
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Temperature Integrity

How Critical Kare Pharma Protects Your Medicine In Transit

Biologic cancer drugs like Keytruda and Herceptin degrade if exposed to high heat or freezing cold. Here is how our certified cold-chain protocol ensures 100% therapeutic potency.

Vacuum Insulated Panels

High-density VIP packaging insulates against desert heat or sub-zero baggage holds, maintaining 2°C-8°C for up to 120 hours.

Phase-Change Coolant Packs

Unlike ordinary melting ice, phase-change gel packs hold precise target temperatures without accidental freezing.

TempTale USB Data Loggers

Every shipment includes a continuous digital temperature logger. Plug into any USB port to verify complete cold-chain history.

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Request Price Quote & Availability

Need Keytruda, Herceptin, or another specialty oncology medication? Share your prescription details and our pharmacy team will provide an authenticated price quote with cold-chain shipping.

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Frequently Asked Questions on Medicine Storage

Yes, absolutely. Keytruda is a monoclonal antibody (biologic protein) that denatures if exposed to warm temperatures. It must be kept continuously refrigerated at 2°C to 8°C (36°F to 46°F) in its original box to shield it from light. Never freeze it, as ice crystals destroy the protein structure.

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